Arcueid Brunestud

As the executioner, she did not have any vampiric impulses, and the rest of the True Ancestors also believed she had none. A priest from the church seeking perfect immortality, Michael Roa Valdamjong, needed to become a Dead Apostle to continue his research as he had already reached the potential of his human body. Arcueid, ignorant of her nature as a vampire and the consequences of drinking blood, was easily tricked by Roa into drinking his and turned berserk, wiping out most of the True Ancestors, turning Roa into one of the strongest Dead Apostles and having a considerable portion of her power stolen by him, before she managed to regain her sanity long enough to chain herself to the throne and go to sleep. From then on she had to suppress her urge to drink blood like any other True Ancestors. The rest of the True Ancestors were wiped out either by Roa or the rest of the Dead Apostles, who made a game of trying to assassinate their creators.

Arcueid finally managed to destroy Roa’s original body, although it took an alliance with the Burial Agency to do it. Roa was not killed however, as he had managed to master reincarnation, and constantly reincarnated into host bodies he chose before his deaths. These host bodies were chosen for a mix of social standing (rich families with influence) and the physical/magical potential of the body. After destroying Roa’s original body, Arcueid went to sleep and awoke only to kill Roa’s re-incarnations constantly, but was never able to destroy him and get her power back as he would simply re-incarnate each time. At the time of Tsukihime, Roa had re-incarnated 17 times, with his last re-incarnation being Tohno SHIKI.