Ookami to Koushinryou: Merchant Meets the Wise Wolf
狼と香辛料
Lawrence is a traveling merchant selling various goods from a horse-drawn cart. One day, he arrives at a village and meets a beautiful girl with the ears and tail of an animal! Her name is Holo the Wisewolf and she brings bountiful harvests. She wishes to return to her homeland, and Lawrence offers to take her. Now, the once-lonely merchant and the once-lonely wisewolf begin their journey north. Source: Crunchyroll
I like the references they did to the end of the manga / ln at the start of ep 1👍
Others cover for the anime can be found here